Synaptic vesicles are “primed” for fast clathrin-mediated endocytosis at the ribbon synapse

@inproceedings{Pelassa2014SynapticVA,
  title={Synaptic vesicles are “primed” for fast clathrin-mediated endocytosis at the ribbon synapse},
  author={Ilaria Pelassa and CongJian Zhao and Mathias Pasche and Benjamin Odermatt and Leon Lagnado},
  booktitle={Front. Mol. Neurosci.},
  year={2014}
}
Retrieval of synaptic vesicles can occur 1-10 s after fusion, but the role of clathrin during this process has been unclear because the classical mode of clathrin-mediated endocytosis (CME) is an order of magnitude slower, as during retrieval of surface receptors. Classical CME is thought to be rate-limited by the recruitment of clathrin, which raises the question: how is clathrin recruited during synaptic vesicle recycling? To investigate this question we applied total internal reflection… CONTINUE READING
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References

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Evidence for a Clathrin

  • J. H. Brandstätter, H. Regus-Leidig
  • 2014

Synaptic vesicles are “primed” for fast clathrin-mediated endocytosis at the ribbon synapse

  • I Citation Pelassa, C Zhao, M Pasche, B Odermatt, L Lagnado
  • Front. Mol. Neurosci. 7:91
  • 2014

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