Synaptic vesicle tethering and the CaV2.2 distal C-terminal

@inproceedings{Wong2014SynapticVT,
  title={Synaptic vesicle tethering and the CaV2.2 distal C-terminal},
  author={Fiona K.Y Wong and Arup R. Nath and Robert Chien-Chung Chen and Sabiha R. Gardezi and Qi Li and Elise F. Stanley},
  booktitle={Front. Cell. Neurosci.},
  year={2014}
}
Evidence that synaptic vesicles (SVs) can be gated by a single voltage sensitive calcium channel (CaV2.2) predict a molecular linking mechanism or "tether" (Stanley, 1993). Recent studies have proposed that the SV binds to the distal C-terminal on the CaV2.2 calcium channel (Kaeser et al., 2011; Wong et al., 2013) while genetic analysis proposed a double tether mechanism via RIM: directly to the C terminus PDZ ligand domain or indirectly via a more proximal proline rich site (Kaeser et al… CONTINUE READING
Highly Cited
This paper has 18 citations. REVIEW CITATIONS
9 Citations
54 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

The morphology of fractions of rat forebrain synapto - somes separated on continuous sucrose density gradients

  • F. K. Wong, Q. Li, E. F. Stanley
  • Biochem . J .
  • 2013
Highly Influential
8 Excerpts

CaV2.2 tethering of synaptic vesicles

  • FK Citation Wong, AR Nath, RHC Chen, SR Gardezi, Q Li, EF Stanley
  • February 2014; published online:
  • 2014

Are unreliable release

  • M. Dittrich, S. D. Meriney
  • 2013

Similar Papers

Loading similar papers…