Synaptic transmission mediated by internal calcium stores in rod photoreceptors.

@article{Suryanarayanan2006SynapticTM,
  title={Synaptic transmission mediated by internal calcium stores in rod photoreceptors.},
  author={Anuradha Suryanarayanan and Malcolm M Slaughter},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2006},
  volume={26 6},
  pages={1759-66}
}
Retinal rod photoreceptors are depolarized in darkness to approximately -40 mV, a state in which they maintain sustained glutamate release despite low levels of calcium channel activation. Blocking voltage-gated calcium channels or ryanodine receptors (RyRs) at the rod presynaptic terminal suppressed synaptic communication to bipolar cells. Spontaneous synaptic events were also inhibited when either of these pathways was blocked. This indicates that both calcium influx and calcium release from… CONTINUE READING
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