Synaptic transmission: Exciting times for presynaptic receptors

@article{Vitten2001SynapticTE,
  title={Synaptic transmission: Exciting times for presynaptic receptors},
  author={Harald Vitten and Jeffry S. Isaacson},
  journal={Current Biology},
  year={2001},
  volume={11},
  pages={R695-R697}
}
Presynaptic receptors play an important role - typically inhibitory--in modulating the strength of synaptic transmission in the brain. Recent studies now reveal that neurotransmitters can enhance synaptic strength by activating ligand-gated ion channels in presynaptic nerve endings.