Synaptic tagging and capture: a bridge from molecular to behaviour

@inproceedings{Ziegler2011SynapticTA,
  title={Synaptic tagging and capture: a bridge from molecular to behaviour},
  author={Lorric Ziegler and Wulfram Gerstner},
  booktitle={BMC Neuroscience},
  year={2011}
}
Hippocampal plasticity is now widely accepted as being the substrate for episodic memory formation. More specifically, several studies in area CA1 of the hippocampus support the Synaptic Tagging and Capture hypothesis (STC) which describes the induction as well as the consolidation phases of synaptic Long-Term Potentiation/Depression (LTP/D) (for a review see [1]). In this framework, initial changes in the synaptic weights require an external signal, sometimes called 3 factor, in order to… CONTINUE READING