Synaptic protein degradation as a mechanism in memory reorganization.

@article{Kaang2009SynapticPD,
  title={Synaptic protein degradation as a mechanism in memory reorganization.},
  author={Bong-Kiun Kaang and Sue-Hyun Lee and Hyoung Kook Kim},
  journal={The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry},
  year={2009},
  volume={15 5},
  pages={430-5}
}
An accumulating body of evidence shows that reactivated long-term memory undergoes a dynamic process called reconsolidation, in which de novo protein synthesis is required to maintain the memory. These findings open up a new dimension in the field of memory research. However, few studies have shown how once-consolidated memory becomes labile. The authors' recent findings have demonstrated that pre-existing long-term memory becomes unstable via the ubiquitin/ proteasome-dependent protein… CONTINUE READING
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