Synaptic plasticity in the basolateral amygdala in transgenic mice expressing dominant-negative cAMP response element-binding protein (CREB) in forebrain.

@article{Rammes2000SynapticPI,
  title={Synaptic plasticity in the basolateral amygdala in transgenic mice expressing dominant-negative cAMP response element-binding protein (CREB) in forebrain.},
  author={Gerhard Rammes and Thomas Steckler and Adelheid Kresse and Guenther Schuetz and Walter Zieglg{\"a}nsberger and Beat Lutz},
  journal={The European journal of neuroscience},
  year={2000},
  volume={12 7},
  pages={
          2534-46
        }
}
Electrophysiological and behavioural experiments were performed in transgenic mice expressing a dominant-negative form of cAMP response element-binding protein (CREBA133) in the limbic system. In control littermate in vitro slice preparation, tetanizing the lateral amygdala-basolateral amygdala (BLA) pathway with a single train (100 Hz for 1 s) produced short-term potentiation (STP) in the BLA. Five trains (10-s interstimulus interval) induced long-term potentiation (LTP), which was completely… CONTINUE READING
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