Synaptic plasticity in the basal ganglia.

  title={Synaptic plasticity in the basal ganglia.},
  author={Jeffery R. Wickens},
  journal={Behavioural brain research},
  volume={199 1},
Activity-dependent synaptic plasticity occurs in several parts of the basal ganglia. Increasing evidence supports the hypothesis that activity-dependent plasticity underlies the acquisition, maintenance, and extinction of certain types of learning in the basal ganglia. This review focuses on synaptic plasticity in the corticostriatal pathway. As in other systems, both long-term potentiation and long-term depression have been described, and intracellular calcium signalling plays an important… CONTINUE READING