Synaptic plasticity associated with a memory engram in the basolateral amygdala.

@article{Nonaka2014SynapticPA,
  title={Synaptic plasticity associated with a memory engram in the basolateral amygdala.},
  author={Ayako Nonaka and Takeshi Toyoda and Yuki Miura and Natsuko Hitora-Imamura and Masamitsu Naka and Megumi Eguchi and Shun Yamaguchi and Yuji Ikegaya and Norio Matsuki and Hiroshi Nomura},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2014},
  volume={34 28},
  pages={9305-9}
}
Synaptic plasticity is a cellular mechanism putatively underlying learning and memory. However, it is unclear whether learning induces synaptic modification globally or only in a subset of neurons in associated brain regions. In this study, we genetically identified neurons activated during contextual fear learning and separately recorded synaptic efficacy from recruited and nonrecruited neurons in the mouse basolateral amygdala (BLA). We found that the fear learning induces presynaptic… CONTINUE READING
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