Synaptic plasticity: taming the beast

  title={Synaptic plasticity: taming the beast},
  author={L. F. Abbott and Sacha B. Nelson},
  journal={Nature Neuroscience},
  volume={3 Suppl 1},
Synaptic plasticity provides the basis for most models of learning, memory and development in neural circuits. To generate realistic results, synapse-specific Hebbian forms of plasticity, such as long-term potentiation and depression, must be augmented by global processes that regulate overall levels of neuronal and network activity. Regulatory processes are often as important as the more intensively studied Hebbian processes in determining the consequences of synaptic plasticity for network… CONTINUE READING
Highly Influential
This paper has highly influenced 105 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 860 extracted citations

The interplay of plasticity and adaptation in neural circuits: a generative model

Front. Synaptic Neurosci. • 2014
View 11 Excerpts
Highly Influenced

0 Hebbian Learning and Plasticity

View 15 Excerpts
Highly Influenced

Spike-based learning in VLSI networks of integrate-and-fire neurons

2007 IEEE International Symposium on Circuits and Systems • 2007
View 6 Excerpts
Highly Influenced

Fault-Tolerant Learning in Spiking Astrocyte-Neural Networks on FPGAs

2018 31st International Conference on VLSI Design and 2018 17th International Conference on Embedded Systems (VLSID) • 2018
View 9 Excerpts
Highly Influenced

Boltzmann machines for time-series

ArXiv • 2017
View 6 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 48 references

Activity co - regulates quantal AMPA and NMDA currents at neocortical synapses

A. J. Watt, M. C. W. van Rossum, K. M. MacLeod, S. B. Nelson, G. G. Turrigiano
Neuron • 2000

Synchrony generation in recurrent networks with frequency-dependent synapses.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2000

Distinct functional types of associative long-term potentiation in neocortical and hippocampal pyramidal neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1999

Similar Papers

Loading similar papers…