Synaptic modulation in pain pathways.

@article{Zeilhofer2005SynapticMI,
  title={Synaptic modulation in pain pathways.},
  author={Hanns Ulrich Zeilhofer},
  journal={Reviews of physiology, biochemistry and pharmacology},
  year={2005},
  volume={154},
  pages={
          73-100
        }
}
  • H. Zeilhofer
  • Published 2005
  • Biology
  • Reviews of physiology, biochemistry and pharmacology
All higher organisms possess a sensory system that allows them to detect potentially tissue-damaging (or noxious) stimuli. The proper functioning of this system is essential to protect their bodies from tissue damage. However, under pathological conditions after severe tissue injury and in inflammatory or neuropathic diseases, this system can become sensitized, and pain can then turn into a disease. Such exaggerated pain sensation (or hyperalgesia) can arise at different levels of integration… 
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