Synaptic modulation by astrocytes via Ca2+-dependent glutamate release

@article{Santello2009SynapticMB,
  title={Synaptic modulation by astrocytes via Ca2+-dependent glutamate release},
  author={Mirko Santello and A. Volterra},
  journal={Neuroscience},
  year={2009},
  volume={158},
  pages={253-259}
}
  • Mirko Santello, A. Volterra
  • Published 2009
  • Biology, Medicine
  • Neuroscience
  • In the past 15 years the classical view that astrocytes play a relatively passive role in brain function has been overturned and it has become increasingly clear that signaling between neurons and astrocytes may play a crucial role in the information processing that the brain carries out. This new view stems from two seminal observations made in the early 1990s: 1. astrocytes respond to neurotransmitters released during synaptic activity with elevation of their intracellular Ca2+ concentration… CONTINUE READING
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