Synaptic localization of GABA(A) receptor subunits in the substantia nigra of the rat: effects of quinolinic acid lesions of the striatum.

@article{Fujiyama2002SynapticLO,
  title={Synaptic localization of GABA(A) receptor subunits in the substantia nigra of the rat: effects of quinolinic acid lesions of the striatum.},
  author={Fumino Fujiyama and F Anne Stephenson and J. Paul Bolam},
  journal={The European journal of neuroscience},
  year={2002},
  volume={15 12},
  pages={1961-75}
}
The inhibitory amino acid, gamma-aminobutyric acid (GABA), plays a critical role in the substantia nigra (SN) in health and disease. GABA transmission is controlled in part by the type(s) of GABA receptor expressed, their subunit composition and their location in relation to GABA release sites. In order to define the subcellular localization of GABA(A) receptors in the SN in normal and pathological conditions, sections of SN from control rats and rats that had received quinolinic acid lesions… CONTINUE READING
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