Synaptic facilitation in Aplysia explored by random presynaptic stimulation

  title={Synaptic facilitation in Aplysia explored by random presynaptic stimulation},
  author={J. P. Kroeker},
  journal={The Journal of General Physiology},
  pages={747 - 763}
The identified interneuron L10 in the abdominal ganglion of Aplysia was stimulated to fire action potentials in a random sequence while the early inhibitory potential of its follower cell L2 was recorded. Application of Wiener nonlinear analysis to these data yielded a predictive model of the facilitating postsynaptic potential. The model shows that facilitation changes both the time-course and the magnitude of the early synaptic potential. The facilitated response has a longer duration than… CONTINUE READING

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