Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors.

@article{Dangelo1995SynapticEO,
  title={Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors.},
  author={Emanuela D'angelo and Giovanna de Filippi and Paola Rossi and Vanni Taglietti},
  journal={The Journal of physiology},
  year={1995},
  volume={484 ( Pt 2)},
  pages={397-413}
}
1. Current-clamp recordings were made in whole-cell patch-clamp configuration from ninety-one granule cells in parasagittal cerebellar slices obtained from 21- to 31-day-old rats. Recordings were performed at 30 degrees C. 2. Resting membrane potential was -58 +/- 6 mV (n = 43). The membrane voltage response to step current injection showed inward rectification consistent with increasing input resistance during membrane depolarization. Over -35 +/- 7 mV (n = 14) repetitive firing with little or… CONTINUE READING
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