Synaptic biology of barrel cortex circuit assembly.

  title={Synaptic biology of barrel cortex circuit assembly.},
  author={Ilaria Vitali and Denis Jabaudon},
  journal={Seminars in cell & developmental biology},
Mature neuronal circuits arise from the coordinated interplay of cell-intrinsic differentiation programs, target-derived signals and activity-dependent processes. Typically, cell-intrinsic mechanisms predominate at early stages of differentiation, while input-dependent processes modulate circuit formation at later stages of development. The whisker barrel cortex of rodents is particularly well suited to study this latter phase. During the first few days after birth, thalamocortical axons (TCA… CONTINUE READING