Synaptic amplification by dendritic spines enhances input cooperativity

@inproceedings{Harnett2012SynapticAB,
  title={Synaptic amplification by dendritic spines enhances input cooperativity},
  author={Mark T. Harnett and Judit K. Makara and Nelson Spruston and William L. Kath and Jeffrey C Magee},
  booktitle={Nature},
  year={2012}
}
Dendritic spines are the nearly ubiquitous site of excitatory synaptic input onto neurons and as such are critically positioned to influence diverse aspects of neuronal signalling. Decades of theoretical studies have proposed that spines may function as highly effective and modifiable chemical and electrical compartments that regulate synaptic efficacy, integration and plasticity. Experimental studies have confirmed activity-dependent structural dynamics and biochemical compartmentalization by… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 118 CITATIONS, ESTIMATED 75% COVERAGE

Biochemical Computation for Spine Structural Plasticity

VIEW 5 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Electrodiffusion models of synaptic potentials in dendritic spines

Thibault Lagache, Krishna Jayant, Rafael Yuste
  • Journal of Computational Neuroscience
  • 2019
VIEW 5 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

Sodium Dynamics in Pyramidal Neuron Dendritic Spines: Synaptically Evoked Entry Predominantly through AMPA Receptors and Removal by Diffusion.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2017
VIEW 4 EXCERPTS
CITES BACKGROUND, METHODS & RESULTS
HIGHLY INFLUENCED

EPSPs Measured in Proximal Dendritic Spines of Cortical Pyramidal Neurons123

VIEW 10 EXCERPTS
CITES BACKGROUND, METHODS & RESULTS
HIGHLY INFLUENCED

Role of Ventral Subiculum in Context-Induced Relapse to Alcohol Seeking after Punishment-Imposed Abstinence.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2016
VIEW 3 EXCERPTS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2012
2019

CITATION STATISTICS

  • 19 Highly Influenced Citations

  • Averaged 11 Citations per year from 2017 through 2019

References

Publications referenced by this paper.