Synaptic Targeting of Kainate Receptors.

@article{PalaciosFilardo2016SynapticTO,
  title={Synaptic Targeting of Kainate Receptors.},
  author={Jon Palacios-Filardo and M Isabel Aller and Juan Lerma},
  journal={Cerebral cortex},
  year={2016},
  volume={26 4},
  pages={1464-72}
}
When native and recombinant kainate receptors (KARs) are compared, there is a mismatch in several of their functional properties. While both generate currents, synaptic responses mediated by KARs have rarely observed in cultured hippocampal neurons. The recent discovery of auxiliary proteins for KARs, such as Netos, offers an explanation for these discrepancies. We found that the GluK5 KAR subunit and the ancillary proteins, Neto1 and Neto2, are not expressed by hippocampal neurons in culture… CONTINUE READING
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Neto1 is an auxiliary subunit of native synaptic kainate receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2011
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The auxiliary subunits Neto1 and Neto2 reduce voltage-dependent inhibition of recombinant kainate receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2012

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