Synaptic Scaling Stabilizes Persistent Activity Driven by Asynchronous Neurotransmitter Release

@article{Volman2011SynapticSS,
  title={Synaptic Scaling Stabilizes Persistent Activity Driven by Asynchronous Neurotransmitter Release},
  author={V. Volman and R. C. Gerkin},
  journal={Neural Computation},
  year={2011},
  volume={23},
  pages={927-957}
}
Small networks of cultured hippocampal neurons respond to transient stimulation with rhythmic network activity (reverberation) that persists for several seconds, constituting an in vitro model of synchrony, working memory, and seizure. This mode of activity has been shown theoretically and experimentally to depend on asynchronous neurotransmitter release (an essential feature of the developing hippocampus) and is supported by a variety of developing neuronal networks despite variability in the… Expand
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