Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms

@article{Citri2008SynapticPM,
  title={Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms},
  author={Ami Citri and Robert C Malenka},
  journal={Neuropsychopharmacology},
  year={2008},
  volume={33},
  pages={18-41}
}
Experiences, whether they be learning in a classroom, a stressful event, or ingestion of a psychoactive substance, impact the brain by modifying the activity and organization of specific neural circuitry. A major mechanism by which the neural activity generated by an experience modifies brain function is via modifications of synaptic transmission; that is, synaptic plasticity. Here, we review current understanding of the mechanisms of the major forms of synaptic plasticity at excitatory… CONTINUE READING
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