Synaptic Connectivity of a Low Density Patterned Neuronal Network Produced on the Poly-L-Lysine Stamped Microelectrode Array

Abstract

Rectangular networks of rat hippocampal neurons have been produced on microelectrode arrays (MEAs). The crossing points of networks were located at the recording electrode sites by aligned microcontact printing (muCP) technique. Polydimethysiloxane (PDMS) stamp was fabricated to print fine poly-L-lysine (PLL) patterns of 2 mum-width lines for neurites and… (More)

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