Synapse-specific reconsolidation of distinct fear memories in the lateral amygdala

@article{Doyre2007SynapsespecificRO,
  title={Synapse-specific reconsolidation of distinct fear memories in the lateral amygdala},
  author={Val{\'e}rie Doy{\`e}re and Jacek Debiec and Marie H Monfils and Glenn E. Schafe and Joseph E LeDoux},
  journal={Nature Neuroscience},
  year={2007},
  volume={10},
  pages={414-416}
}
When reactivated, memories enter a labile, protein synthesis–dependent state, a process referred to as reconsolidation. Here, we show in rats that fear memory retrieval produces a synaptic potentiation in the lateral amygdala that is selective to the reactivated memory, and that disruption of reconsolidation is correlated with a reduction of synaptic potentiation in the lateral amygdala. Thus, both retrieval and reconsolidation alter memories via synaptic plasticity at selectively targeted… 

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