Synapse alterations in autism: Review of animal model findings.

  title={Synapse alterations in autism: Review of animal model findings.},
  author={Martina Zatkova and Jan Bakos and J{\'u}lius Hodosy and Daniela Ostatn{\'i}kov{\'a}},
  journal={Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia},
  volume={160 2},
BACKGROUND Recent research has produced an explosion of experimental data on the complex neurobiological mechanisms of developmental disorders including autism. Animal models are one approach to studying the phenotypic features and molecular basis of autism. In this review, we describe progress in understanding synaptogenesis and alterations to this process with special emphasis on the cell adhesion molecules and scaffolding proteins implicated in autism. Genetic mouse model experiments are… CONTINUE READING
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