Synapse-Aware Skeleton Generation for Neural Circuits

  title={Synapse-Aware Skeleton Generation for Neural Circuits},
  author={Brian Matejek and D. Wei and Xueying Wang and J. Zhao and K. Pal{\'a}gyi and H. Pfister},
Reconstructed terabyte and petabyte electron microscopy image volumes contain fully-segmented neurons at resolutions fine enough to identify every synaptic connection. After manual or automatic reconstruction, neuroscientists want to extract wiring diagrams and connectivity information to analyze the data at a higher level. Despite significant advances in image acquisition, neuron segmentation, and synapse detection techniques, the extracted wiring diagrams are still quite coarse, and often do… Expand
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