Synapse‐to‐synapse variation in mean synaptic vesicle size and its relationship with synaptic morphology and function

  title={Synapse‐to‐synapse variation in mean synaptic vesicle size and its relationship with synaptic morphology and function},
  author={Lei Qu and Yulia Akbergenova and Yunming Hu and Thomas Schikorski},
  journal={Journal of Comparative Neurology},
Synaptic vesicle (SV) size is one parameter that controls the amount of neurotransmitter released from individual SVs and, therefore, is fundamental to our understanding of synaptic function. The recently discovered variability of mean SV size among excitatory hippocampal synapses—if actively regulated—is a potential mechanism for the regulation of transmitter release. Here, we investigated which parameters influence mean SV size. First, we revealed that synapse‐to‐synapse variability of SV… 
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