Symptoms as predictors of response in depression.

  title={Symptoms as predictors of response in depression.},
  author={S W Burton},
  journal={Journal of psychopharmacology},
  volume={7 1},
Sertraline, a novel selective serotonin re-uptake inhibitor, has been proven as effective as amitriptyline and imipramine, and more effective than placebo, in double-blind controlled studies in patients with major depressive disorder. The question 'Do symptoms predict response to treatment?' is an important one in clinical practice. In order to try and answer this question, four double-blind clinical trials in major depressive disorder have been examined for clinically important symptoms and… CONTINUE READING