Symptomatic hypogammaglobulinemia in infancy and childhood – clinical outcome and in vitro immune responses

@article{Kidon2004SymptomaticHI,
  title={Symptomatic hypogammaglobulinemia in infancy and childhood – clinical outcome and in vitro immune responses},
  author={Mona Kidon and Zeev Theodor Handzel and Rivka Schwartz and Irit Altboum and Michael V. Stein and Israel Zan-Bar},
  journal={BMC Family Practice},
  year={2004},
  volume={5},
  pages={23 - 23}
}
BACKGROUND Symptomatic hypogammaglobulinemia in infancy and childhood (SHIC), may be an early manifestation of a primary immunodeficiency or a maturational delay in the normal production of immunoglobulins (Ig). We aimed to evaluate the natural course of SHIC and correlate in vitro lymphoproliferative and secretory responses with recovery of immunoglobulin values and clinical resolution. METHODS Children, older than 1 year of age, referred to our specialist clinic because of recurrent… CONTINUE READING
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