Symptomatic and urodynamic responses in patients with reduced or no seminal emission during silodosin treatment for LUTS and BPH

@inproceedings{Roehrborn2011SymptomaticAU,
  title={Symptomatic and urodynamic responses in patients with reduced or no seminal emission during silodosin treatment for LUTS and BPH},
  author={Claus G. Roehrborn and Simona Kaplan and Herbert Lepor and Weining Volinn},
  booktitle={Prostate Cancer and Prostatic Diseases},
  year={2011}
}
Data from phase 3 studies (NCT00224107, NCT00224120) of silodosin for treatment of BPH symptoms were analyzed to examine the relationship between treatment efficacy and occurrence of abnormal ejaculation. Men aged ⩾50 years with International Prostate Symptom Scores (IPSS) ⩾13 and peak urinary flow rates (Qmax) of 4–15 ml s−1 received placebo or silodosin 8 mg once daily for 12 weeks. Silodosin-treated patients were stratified by absence or presence of ‘retrograde ejaculation’ (RE). Groups were… CONTINUE READING