Symptom dimensions and brain morphology in schizophrenia and related psychotic disorders.

@article{Flaum1995SymptomDA,
  title={Symptom dimensions and brain morphology in schizophrenia and related psychotic disorders.},
  author={Michael A Flaum and Daniel S. O'Leary and Victor W Swayze and Del D. Miller and Stephan V. Arndt and Nancy C. Andreasen},
  journal={Journal of psychiatric research},
  year={1995},
  volume={29 4},
  pages={261-76}
}
The heterogeneity of symptoms in schizophrenia may reflect heterogeneity of underlying pathophysiological mechanisms. Factor analytic studies have consistently identified three symptom factors, psychotic, negative and disorganized, as independent dimensions of schizophrenic psychopathology. This study examined the relationship of these symptom dimensions with volumes of specific brain regions. One-hundred and sixty-six schizophrenia spectrum patients were clinically evaluated with the… CONTINUE READING