Symposium 6 : Adipose tissue – liver – muscle interactions leading to insulin resistance Metabolic flexibility

@inproceedings{Storlien2004Symposium6,
  title={Symposium 6 : Adipose tissue – liver – muscle interactions leading to insulin resistance Metabolic flexibility},
  author={Len H. Storlien and Nick D. Oakes and David E Kelley},
  year={2004}
}
Human physiology needs to be well adapted to cope with major discontinuities in both the supply of and demand for energy. This adaptability requires ‘a clear capacity to utilize lipid and carbohydrate fuels and to transition between them’ (Kelley et al. 2002b). Such capacities characterize the healthy state and can be termed ‘metabolic flexibility’. However, increasing evidence points to metabolic inflexibility as a key dysfunction of the cluster of disease states encompassed by the term… CONTINUE READING