Sympathetically mediated hypertension caused by chronic inhibition of nitric oxide.

@article{Sander1995SympatheticallyMH,
  title={Sympathetically mediated hypertension caused by chronic inhibition of nitric oxide.},
  author={Michael Sander and Phyllis Hansen and Ronald G. Victor},
  journal={Hypertension},
  year={1995},
  volume={26 4},
  pages={691-5}
}
Pharmacological inhibition of nitric oxide synthase causes sustained hypertension in many animal species. Although this hypertension has been attributed to inhibition of endothelium-dependent vasodilation, short-term studies in anesthetized preparations have advanced the hypothesis that there could be a sympathetic component to this hypertension. To test this hypothesis we measured intra-arterial pressure directly before and after 1 week of treatment with the nitric oxide synthesis inhibitor N… CONTINUE READING

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