Sympathetic regulation of the cerebral circulation by the carotid chemoreceptor reflex.

  title={Sympathetic regulation of the cerebral circulation by the carotid chemoreceptor reflex.},
  author={Stephen F. Vatner and Luigi Priano and John D. Rutherford and W. Thomas Manders},
  journal={The American journal of physiology},
  volume={238 4},
The effects of carotid chemoreceptor reflex stimulation (intracarotid injection of nicotine 0.2 microgram/kg) were examined in conscious dogs on the cerebral circulation, using the radioactive microsphere technique to measure cerebral blood flow. In intact dogs (n = 18) with ventilation controlled, carotid chemoreceptor reflex stimulation increased (P less than 0.01) mean arterial pressure by 36 +/- 5% (SE) and calculated cerebral vascular resistance by 58 +/- 13%, whereas cerebral blood flow… CONTINUE READING


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