Sympathetic nerves protect against blood-brain barrier disruption in the spontaneously hypertensive rat.

@article{Mueller1982SympatheticNP,
  title={Sympathetic nerves protect against blood-brain barrier disruption in the spontaneously hypertensive rat.},
  author={S. Dinheiro Machado Mueller and Phillip J. Ertel and David L. Felten and J. Marc Overhage},
  journal={Stroke},
  year={1982},
  volume={13 1},
  pages={
          83-8
        }
}
SUMMARY The cerebral vessels of spontaneously hypertensive rats (SHR) are reported to have an in­ creased luminal size and decreased wall thickness after chronic sympathetic denervation. In order to evaluate a possible physiological significance of this observation, we studied blood-brain barrier protein transfer in two month old SHR and their normotensive controls, Wistar-Kyoto (WKY), during profound vasodilation stimuli one month after a unilateral superior cervical ganglionectomy. Our… CONTINUE READING

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