Sympathetic nerve function and vascular reactivity in spontaneously hypertensive rats.


Increased neurotransmitter release during sympathetic nerve stimulation may contribute importantly to the maintenance of spontaneous hypertension. Therefore, transmitter release and vascular reactivity were measured in perfused mesenteric vasculature of spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto rats (WKY). Increase in norepinephrine… (More)