Sympathetic nerve activity in obstructive sleep apnoea.

  title={Sympathetic nerve activity in obstructive sleep apnoea.},
  author={Krzysztof Narkiewicz and V. K. Somers},
  journal={Acta physiologica Scandinavica},
  volume={177 3},
The mechanisms underlying the link between obstructive sleep apnoea (OSA) and cardiovascular disease are not completely established. However, there is increasing evidence that autonomic mechanisms are implicated. A number of studies have consistently shown that patients with OSA have high levels of sympathetic nerve traffic. During sleep, repetitive episodes of hypoxia, hypercapnia and obstructive apnoea act through chemoreceptor reflexes and other mechanisms to increase sympathetic drive… CONTINUE READING