Sympathetic hyperactivity in patients with ulcerative colitis


Hypo and hyperactivity of the autonomic nervous system have been associated with chronic bowel inflammation diseases. We investigated the autonomic function in 11 patients with chronic ulcerative colitis (UC) and 17 healthy controls by means of cardiovascular autonomic tests and heart rate variability. Autonomic responses were normal in patients and controls. At rest, LF/HF ratios were significantly (P < 0.05) higher in chronic UC patients (2.4 ± 1.6) compared to controls (1.2 ± 1.0). Our results suggest a higher sympathetic tone at rest in patients with chronic UC.

DOI: 10.1007/s10286-007-0425-0

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@article{Maule2007SympatheticHI, title={Sympathetic hyperactivity in patients with ulcerative colitis}, author={Simona Maule and Giulia Pierangeli and Sabina Cevoli and Daniela Grimaldi and Paolo Gionchetti and G Barbara and Fernando Rizzello and Vincenzo Stanghellini and Roberto Corinaldesi and Massimo Campieri and Prof. Pietro Cortelli}, journal={Clinical Autonomic Research}, year={2007}, volume={17}, pages={217-220} }