Sympathetic hyperactivity after traumatic brain injury and the role of beta-blocker therapy.

@article{Heffernan2010SympatheticHA,
  title={Sympathetic hyperactivity after traumatic brain injury and the role of beta-blocker therapy.},
  author={Daithi S. Heffernan and Kenji Inaba and Saman Arbabi and Bryan Alan Cotton},
  journal={The Journal of trauma},
  year={2010},
  volume={69 6},
  pages={
          1602-9
        }
}
Head injury remains the leading cause of death among trauma patients and accounts for one-third of all trauma mortalities.1,2 Of these, 75% will die within the first 3 days. In patients who survive beyond this period, however, the underlying causes of death are the result of non-neurologic organ dys 
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Administration of beta blockers after TBI was associated with improved survival, before and after adjusting for the more severe injuries observed in the treatment cohort.
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TLDR
This meta-analysis demonstrated that administration of β-blockers after TBI was safe and effective and may therefore be suggested in the TBI care, however, more high-quality trials are needed to investigate the use of β -blockers in the management of TBI.
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