Sympathetic control of the cardiovascular response to acute hypoxemia in the chick embryo.

@article{Mulder2002SympatheticCO,
  title={Sympathetic control of the cardiovascular response to acute hypoxemia in the chick embryo.},
  author={A. L. M. Twan Mulder and Annemieke Miedema and Jo G. R. De Mey and Dino A Giussani and Carlos E. Blanco},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2002},
  volume={282 4},
  pages={R1156-63}
}
In response to an acute hypoxemic insult, the mammalian fetus shows a redistribution of the cardiac output in favor of the heart and brain. Peripheral vasoconstriction contributes to this response and is partly mediated by the release of catecholamines. Two mechanisms of catecholamine release in the fetus are reported: 1) neurogenic sympathetic stimulation and 2) a nonneurogenic mechanism via a direct effect of hypoxemia on chromaffin tissues. In the present study, the effects of sympathetic… CONTINUE READING