Sympathetic changes during development of cardiac hypertrophy in aortic-constricted rats.

@article{Siri1988SympatheticCD,
  title={Sympathetic changes during development of cardiac hypertrophy in aortic-constricted rats.},
  author={Françoise Siri},
  journal={The American journal of physiology},
  year={1988},
  volume={255 3 Pt 2},
  pages={H452-7}
}
Cardiac hypertrophy is frequently associated with sympathetic changes that include increased myocardial norepinephrine turnover, depleted myocardial norepinephrine stores, decreased myocardial responses to sympathetic nerve stimulation, and elevated plasma catecholamines. To better understand these events mechanistically, the time course of each was assessed in rat hearts subjected to aortic constriction-induced pressure overload. There was no evidence of increased left ventricular… CONTINUE READING

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