Sympathetic activation: a mechanism for morphine induced pain and rises in liver enzymes after cholecystectomy?

@article{RobertsThomson1990SympatheticAA,
  title={Sympathetic activation: a mechanism for morphine induced pain and rises in liver enzymes after cholecystectomy?},
  author={Ian C. Roberts-Thomson and Julie R. Jonsson and Derek B. Frewin and Geoffrey Coates},
  journal={Gut},
  year={1990},
  volume={31 2},
  pages={217-21}
}
In patients with biliary type pain after cholecystectomy, morphine often precipitates pain and may induce rises in plasma concentrations of liver enzymes because of exaggerated or prolonged rises in intrabiliary pressure. In this study, changes in plasma concentrations of catecholamines and histamine were determined after the administration of morphine in patients with and without a two-fold or greater rise in the plasma concentration of aspartate aminotransferase at four hours. Those showing… CONTINUE READING