Sympathetic Nervous System Dysfunction in Fibromyalgia, Chronic Fatigue Syndrome, Irritable Bowel Syndrome, and Interstitial Cystitis: A Review of Case-Control Studies

  title={Sympathetic Nervous System Dysfunction in Fibromyalgia, Chronic Fatigue Syndrome, Irritable Bowel Syndrome, and Interstitial Cystitis: A Review of Case-Control Studies},
  author={L. A. Mart{\'i}nez-Mart{\'i}nez and Tania Mora and Ang{\'e}lica Vargas and Mario Fuentes-Iniestra and Manuel Mart{\'i}nez-Lav{\'i}n},
  journal={JCR: Journal of Clinical Rheumatology},
Background Fibromyalgia often coexists and overlaps with other syndromes such as chronic fatigue, irritable bowel syndrome, and interstitial cystitis. Chronic stress has been implicated in the pathogenesis of these illnesses. The sympathetic nervous system is a key element of the stress response system. Sympathetic dysfunction has been reported in these syndromes, raising the possibility that such dysautonomia could be their common clustering underlying pathogenesis. Objective The objective of… 

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