Syk to death.

Abstract

A lthough normal B-cell development depends on the expression of a functional B-cell receptor (BCR) on the cell surface, the degree to which established tumors depend on its continued signaling is unclear. While early (pre-B) and late (plasma cell) tumors would not appear to depend on this signal, there are a number of tumors in between that clearly do. The… (More)
DOI: 10.1182/blood-2008-12-191510

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