Switching to duloxetine in selective serotonin reuptake inhibitor non- and partial-responders: effects on painful physical symptoms of depression.

@article{Perahia2009SwitchingTD,
  title={Switching to duloxetine in selective serotonin reuptake inhibitor non- and partial-responders: effects on painful physical symptoms of depression.},
  author={David Perahia and Deborah C Quail and Durisala Desaiah and {\'A}ngel L Montejo and Alan F. Schatzberg},
  journal={Journal of psychiatric research},
  year={2009},
  volume={43 5},
  pages={512-8}
}
Painful physical symptoms (PPS) are common in patients with depression. Our objective was to evaluate the presence of PPS in a sample of SSRI non- or partial-responders with MDD and examine the effect of a switch to duloxetine on those PPS. Outpatients who met criteria for MDD despite having taken an SSRI antidepressant for at least 6 weeks, and who had a Hamilton depression rating scale total score of at least 15 and a clinical global impression of severity score of at least 3, were randomized… CONTINUE READING

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Management of painful physical symptoms associated with depression and mood disorders

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