Switching of flagellar motility in Helicobacter pylori by reversible length variation of a short homopolymeric sequence repeat in fliP, a gene encoding a basal body protein.

@article{Josenhans2000SwitchingOF,
  title={Switching of flagellar motility in Helicobacter pylori by reversible length variation of a short homopolymeric sequence repeat in fliP, a gene encoding a basal body protein.},
  author={Christine Josenhans and Kathryn A. Eaton and Tracy Thevenot and Sebastian Suerbaum},
  journal={Infection and immunity},
  year={2000},
  volume={68 8},
  pages={4598-603}
}
The genome of Helicobacter pylori contains numerous simple nucleotide repeats that have been proposed to have regulatory functions and to compensate for the conspicuous dearth of master regulatory pathways in this highly host-adapted bacterium. H. pylori strain 26695, whose genomic sequence was determined by The Institute for Genomic Research (TIGR), contains a repeat of nine cytidines in the fliP flagellar basal body gene that splits the open reading frame in two parts. In this work, we… CONTINUE READING
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