Swiprosin-1 Is a Novel Actin Bundling Protein That Regulates Cell Spreading and Migration

@inproceedings{Kwon2013Swiprosin1IA,
  title={Swiprosin-1 Is a Novel Actin Bundling Protein That Regulates Cell Spreading and Migration},
  author={Min-Sung Kwon and Kyoung Ryoung Park and Young-Dae Kim and Bo-Ra Na and Hye-Ran Kim and Hak-Jong Choi and Indre Piragyte and Hyesung Jeon and Kyung Hwun Chung and Woo Keun Song and Soo Hyun Eom and Chang-Duk Jun},
  booktitle={PloS one},
  year={2013}
}
Protein functions are often revealed by their localization to specialized cellular sites. Recent reports demonstrated that swiprosin-1 is found together with actin and actin-binding proteins in the cytoskeleton fraction of human mast cells and NK-like cells. However, direct evidence of whether swiprosin-1 regulates actin dynamics is currently lacking. We found that swiprosin-1 localizes to microvilli-like membrane protrusions and lamellipodia and exhibits actin-binding activity. Overexpression… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 18 CITATIONS

EFhd2/swiprosin-1 regulates LPS-induced macrophage recruitment via enhancing actin polymerization and cell migration.

  • International immunopharmacology
  • 2018
VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Swiprosin-1 stimulates cancer invasion and metastasis by increasing the Rho family of GTPase signaling

  • Oncotarget
  • 2015
VIEW 4 EXCERPTS
CITES METHODS, RESULTS & BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 55 REFERENCES

Functional and structural analysis of the conserved EFhd2 protein

Y Ferrer-Acosta, EN Rodriguez Cruz, C Vaquer Adel, IE Vega
  • Protein Pept Lett
  • 2013

Similar Papers

Loading similar papers…