Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters.

@article{Tolstorukov2013SwiSnfCR,
  title={Swi/Snf chromatin remodeling/tumor suppressor complex establishes nucleosome occupancy at target promoters.},
  author={Michael Y. Tolstorukov and Courtney G Sansam and Ping Lu and Edward C. Koellhoffer and Katherine C. Helming and Burak Han Alver and Erik J. Tillman and Julia A Evans and Boris G. Wilson and Peter J. Park and Charles W. M. Roberts},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2013},
  volume={110 25},
  pages={10165-70}
}
Precise nucleosome-positioning patterns at promoters are thought to be crucial for faithful transcriptional regulation. However, the mechanisms by which these patterns are established, are dynamically maintained, and subsequently contribute to transcriptional control are poorly understood. The switch/sucrose non-fermentable chromatin remodeling complex, also known as the Brg1 associated factors complex, is a master developmental regulator and tumor suppressor capable of mobilizing nucleosomes… CONTINUE READING

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