Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract.

  title={Sweet-talk: role of host glycosylation in bacterial pathogenesis of the gastrointestinal tract.},
  author={Anthony P. Moran and Ananya Gupta and Lokesh Joshi},
  volume={60 10},
Glycosylation is a key modification of proteins and lipids and is involved in most intermolecular and intercellular interactions. The gastrointestinal mucus gel is continuous and can be divided into two layers: a secreted loosely associated layer and a layer firmly attached to the mucosa. In addition, the membrane-bound glycosylated proteins and lipids create a glycocalyx, which remains adherent on each cell and is dynamic and responsive to the physiological state and environment of the cell… CONTINUE READING
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