Swe1p Responds to Cytoskeletal Perturbation, Not Bud Size, in S. cerevisiae

@article{McNulty2005Swe1pRT,
  title={Swe1p Responds to Cytoskeletal Perturbation, Not Bud Size, in S. cerevisiae},
  author={John J. McNulty and Daniel J. Lew},
  journal={Current Biology},
  year={2005},
  volume={15},
  pages={2190-2198}
}
BACKGROUND S. cerevisiae cells must grow to a critical size in G1 in order to pass start and enter the cell cycle. A recent study proposed that in addition to the mother size control in G1, the bud must grow to a critical bud size in G2 in order to enter mitosis. Insufficient bud size would cause G2 arrest enforced by the mitotic inhibitor Swe1p, explaining previous findings that some perturbations that block bud growth also trigger Swe1p-dependent cell-cycle arrest. RESULTS We tested the… CONTINUE READING

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