Suxamethonium-induced hyperkalaemia 6 weeks after chemoradiotherapy in a patient with rectal carcinoma.

@article{Holak2007SuxamethoniuminducedH6,
  title={Suxamethonium-induced hyperkalaemia 6 weeks after chemoradiotherapy in a patient with rectal carcinoma.},
  author={Elena J. Holak and Julie Faulkner Connelly and Paul S. Pagel},
  journal={British journal of anaesthesia},
  year={2007},
  volume={98 6},
  pages={
          766-8
        }
}
Suxamethonium causes an efflux of potassium (K+) ions by depolarizing acetylcholine receptors within the neuromuscular junction and produces a transient, small rise in serum K+ concentration in normal individuals that is usually of little clinical importance. Despite the clear efficacy and relative safety of suxamethonium in many patients, anaesthetists are also very aware that acute, severe hyperkalaemia resulting in important cardiovascular sequelae (e.g. malignant ventricular arrhythmias… 
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TLDR
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    Anaesthesia and intensive care
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TLDR
The normal hyperkalaemic response to suxamethonium, the factors affecting it, the conditions in which it may be exaggerated, and the periods of high risk are described.
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TLDR
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TLDR
It is believed that mucositis was a contributing factor to this case of fatal hyperkalemia after administration of succinylcholine, with a mechanism similar to that reported with thermal injury.
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