Sutureless nerve repair with laser-activated chitosan adhesive: a pilot in vivo study.

@article{Lauto2008SuturelessNR,
  title={Sutureless nerve repair with laser-activated chitosan adhesive: a pilot in vivo study.},
  author={Antonio Lauto and Leslie J Foster and Albert P. Avolio and David Sampson and Colin L Raston and Maria Sarris and Gavin Mckenzie and Marcus Stoodley},
  journal={Photomedicine and laser surgery},
  year={2008},
  volume={26 3},
  pages={227-34}
}
OBJECTIVE The anastomosis of peripheral nerves is a demanding procedure that has potential complications due to foreign body reactions elicited by sutures. In this study, the sutureless in vivo anastomosis of rat tibial nerves was successfully performed, using for the first time a chitosan-based laser-activated adhesive. The nerve thermal damage caused by the laser irradiation was quantitatively assessed. MATERIALS AND METHODS A novel adhesive composed of chitosan, indocyanine green, acetic… CONTINUE READING